![New study finds classical RAS proteins are not essential for RAF inhibitor-induced paradoxical ERK activation | Frederick National Laboratory New study finds classical RAS proteins are not essential for RAF inhibitor-induced paradoxical ERK activation | Frederick National Laboratory](https://frederick.cancer.gov/sites/default/files/styles/hero_image_news_article/public/2022-03/KRAS%20RAF1%20study_Image%20copy.png?itok=5Y6nhdR9)
New study finds classical RAS proteins are not essential for RAF inhibitor-induced paradoxical ERK activation | Frederick National Laboratory
![New study finds classical RAS proteins are not essential for RAF inhibitor-induced paradoxical ERK activation | Frederick National Laboratory New study finds classical RAS proteins are not essential for RAF inhibitor-induced paradoxical ERK activation | Frederick National Laboratory](https://frederick.cancer.gov/sites/default/files/styles/social_media_card/public/2022-03/RAF.png?itok=r3bApYrz)
New study finds classical RAS proteins are not essential for RAF inhibitor-induced paradoxical ERK activation | Frederick National Laboratory
![Eurofins DiscoverX A-Raf Protein, Active Quantity: 250 μg Eurofins DiscoverX A-Raf Protein, Active | Fisher Scientific Eurofins DiscoverX A-Raf Protein, Active Quantity: 250 μg Eurofins DiscoverX A-Raf Protein, Active | Fisher Scientific](https://assets.fishersci.com/TFS-Assets/CCG/product-images/GEL%2014-956%20A-Raf.jpg-650.jpg)
Eurofins DiscoverX A-Raf Protein, Active Quantity: 250 μg Eurofins DiscoverX A-Raf Protein, Active | Fisher Scientific
![The RAF family: an expanding network of post-translational controls and protein-protein interactions | Cell Research The RAF family: an expanding network of post-translational controls and protein-protein interactions | Cell Research](https://media.springernature.com/m685/springer-static/image/art%3A10.1038%2Fcr.1998.9/MediaObjects/41422_1998_Article_BFcr19989_Fig1_HTML.jpg)
The RAF family: an expanding network of post-translational controls and protein-protein interactions | Cell Research
![Figure 1 from Meaningful relationships: the regulation of the Ras/Raf/MEK/ERK pathway by protein interactions. | Semantic Scholar Figure 1 from Meaningful relationships: the regulation of the Ras/Raf/MEK/ERK pathway by protein interactions. | Semantic Scholar](https://d3i71xaburhd42.cloudfront.net/a553ba9a74821128e29f081475e76ec7ca0dc4c6/2-Figure1-1.png)
Figure 1 from Meaningful relationships: the regulation of the Ras/Raf/MEK/ERK pathway by protein interactions. | Semantic Scholar
![Structure of the RAF proteins.The RAF-isoforms, A-RAF, B-RAF and C-RAF,... | Download Scientific Diagram Structure of the RAF proteins.The RAF-isoforms, A-RAF, B-RAF and C-RAF,... | Download Scientific Diagram](https://www.researchgate.net/publication/8199334/figure/fig3/AS:267875084664879@1440877805374/Structure-of-the-RAF-proteinsThe-RAF-isoforms-A-RAF-B-RAF-and-C-RAF-share-three.png)
Structure of the RAF proteins.The RAF-isoforms, A-RAF, B-RAF and C-RAF,... | Download Scientific Diagram
![IJMS | Free Full-Text | Selected Approaches to Disrupting Protein– Protein Interactions within the MAPK/RAS Pathway IJMS | Free Full-Text | Selected Approaches to Disrupting Protein– Protein Interactions within the MAPK/RAS Pathway](https://www.mdpi.com/ijms/ijms-24-07373/article_deploy/html/images/ijms-24-07373-g001.png)
IJMS | Free Full-Text | Selected Approaches to Disrupting Protein– Protein Interactions within the MAPK/RAS Pathway
![Autoinhibition in Ras effectors Raf, PI3Kα, and RASSF5: a comprehensive review underscoring the challenges in pharmacological intervention | Biophysical Reviews Autoinhibition in Ras effectors Raf, PI3Kα, and RASSF5: a comprehensive review underscoring the challenges in pharmacological intervention | Biophysical Reviews](https://media.springernature.com/lw685/springer-static/image/art%3A10.1007%2Fs12551-018-0461-0/MediaObjects/12551_2018_461_Fig3_HTML.png)
Autoinhibition in Ras effectors Raf, PI3Kα, and RASSF5: a comprehensive review underscoring the challenges in pharmacological intervention | Biophysical Reviews
![Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer | Oncogene Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer | Oncogene](https://media.springernature.com/full/springer-static/image/art%3A10.1038%2Fsj.onc.1210422/MediaObjects/41388_2007_Article_BF1210422_Fig1_HTML.jpg)
Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer | Oncogene
![B-Raf protein and signaling pathways. The B-Raf protein and its related... | Download Scientific Diagram B-Raf protein and signaling pathways. The B-Raf protein and its related... | Download Scientific Diagram](https://www.researchgate.net/publication/236337146/figure/fig1/AS:202640605618201@1425324693958/B-Raf-protein-and-signaling-pathways-The-B-Raf-protein-and-its-related-signaling-pathway.png)
B-Raf protein and signaling pathways. The B-Raf protein and its related... | Download Scientific Diagram
![Cellular functions of RAF kinases.RAS mediates the activation of A-RAF,... | Download Scientific Diagram Cellular functions of RAF kinases.RAS mediates the activation of A-RAF,... | Download Scientific Diagram](https://www.researchgate.net/publication/8199334/figure/fig5/AS:267971817898004@1440900868364/Cellular-functions-of-RAF-kinasesRAS-mediates-the-activation-of-A-RAF-B-RAF-and-C-RAF.png)